ACS 2025: 212,200 New Melanoma Cases Projected, a Record High
The American Cancer Society projects more melanoma diagnoses than ever in 2025, a sobering reminder that one of the most preventable cancers keeps climbing.
The American Cancer Society's Cancer statistics, 2025 report, published January 16, 2025 in CA: A Cancer Journal for Clinicians, projects 212,200 new US melanoma diagnoses for 2025 (104,960 invasive and 107,240 in situ) and an estimated 8,430 melanoma deaths.
Oncology researchers emphasize that melanoma is largely preventable, with the majority of cases linked to ultraviolet exposure that sun protection and avoiding indoor tanning can reduce.
Questions we get a lot
How many new melanoma cases are projected for 2025?
The American Cancer Society projects 212,200 new melanoma diagnoses in the US for 2025, the highest on record. That breaks down into 104,960 invasive cases and 107,240 in-situ cases. The figures come from the ACS Cancer statistics, 2025 report published in CA: A Cancer Journal for Clinicians.
Is the rise in melanoma just due to better detection?
Improved screening and awareness do contribute to higher in-situ detection, but invasive melanoma incidence has also been climbing, indicating a real increase in disease burden, not just earlier catches. The ACS projects 104,960 invasive cases for 2025 alone. The Melanoma Research Alliance notes the continued upward trend in invasive diagnoses.
How many people are expected to die of melanoma in 2025?
The ACS estimates 8,430 melanoma deaths in the US for 2025. While melanoma accounts for a small share of skin cancers by number, it causes the majority of skin cancer deaths because it can spread if not caught early. This is why early detection and daily UV protection matter.
r/SkincareAddiction: 'Saw a headline that melanoma cases hit a record in 2025. Is that just better detection, or is it actually getting worse?'