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Filter Chemistry & Next-Gen Filters

Ecamsule (Mexoryl SX): L'Oréal's UVA Innovation

The patented filter that gave the US a rare UVA upgrade.

By the numbers

Mexoryl 400 was approved in the EU in 2019 at concentrations up to 3%.

Peaking at 385 nm, Mexoryl 400 covers the deep ultra-long UVA1 range most filters miss, meaning real protection against the wavelengths that drive aging.
What the evidence shows

Frequently asked questions

What is the difference between Mexoryl SX, XL and 400?

All three are L'Oréal/BASF UVA filters. Mexoryl SX (ecamsule) covers shorter UVA; Mexoryl XL (drometrizole trisiloxane) is broad-spectrum and oil-soluble; and Mexoryl 400 (MCE) targets ultra-long UVA1, peaking around 385 nm — the deep wavelengths most older filters miss.

What is bemotrizinol (Parsol Shield)?

Bemotrizinol (trade name Parsol Shield; also known as Tinosorb S) is a broad-spectrum UVA+UVB filter that is highly photostable. On June 9, 2026 the FDA approved it — the first new sunscreen active added to the US monograph since the 1990s — for adults and children 6 months and older at up to 6%.

Are next-gen UV filters better than older ones?

Newer filters such as bemotrizinol, bisoctrizole and Mexoryl 400 generally give broader, more even UVA coverage and far better photostability than older ones like avobenzone, which degrades in sunlight. They also tend to feel more elegant — though applying enough and reapplying still matter most.

What people are asking

r/SkincareScience: 'Why is Mexoryl 400 such a big deal for UVA?'

Sources & citations

  • Wikipedia/CosIng entry, methoxypropylamino cyclohexenylidene ethoxyethylcyanoacetate (MCE)
  • dermapproved.com ↗

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