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Ingredient · INCI reference

Acetyl Hexapeptide-1

A synthetic acetylated hexapeptide used in cosmetics as a skin-conditioning active.

What it is

Acetyl Hexapeptide-1 is a synthetic peptide composed of six amino acids with an acetyl group on the terminal end, which improves its stability. It is used in skincare formulations as a conditioning agent and is typically present at low concentrations. Peptides like this are incorporated for their signaling-style conditioning role within a finished product.

Safety & warnings

Short synthetic peptides are generally well tolerated and used at very low concentrations. As with any cosmetic active, sensitive individuals may wish to patch test, but peptides are not commonly associated with comedogenicity or fragrance allergy.

Origin & sourcing

Synthetic, manufactured through peptide synthesis to produce a defined sequence of amino acids that is then acetylated.

Questions everyone asks

Is acetyl hexapeptide-1 natural or synthetic?

It is a synthetic peptide made by chemically assembling a defined six-amino-acid sequence and adding an acetyl group.

What does it do in a formula?

It serves as a skin-conditioning ingredient and is usually included at low concentrations.

Sources & references

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