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Ingredient · INCI reference

Acetyl Tetrapeptide-5

Acetyl tetrapeptide-5 is a synthetic four-amino-acid peptide used in skincare as a skin-conditioning agent.

What it is

Acetyl tetrapeptide-5 is a short signal-type peptide composed of four amino acids with an acetyl group added to improve stability. It is incorporated into cosmetic formulations, including some sunscreens, as a conditioning ingredient. Like other synthetic peptides it is used at very low concentrations.

Safety & warnings

Acetyl tetrapeptide-5 is generally well tolerated at cosmetic use levels and is not associated with notable allergen or comedogenicity concerns.

Origin & sourcing

Synthetic; produced by peptide synthesis and acetylation.

Questions everyone asks

What kind of ingredient is acetyl tetrapeptide-5?

It is a synthetic short-chain peptide used as a skin-conditioning agent in skincare and sunscreen formulas.

Is it used at high concentrations?

No; peptides like this are typically used in very small amounts within a finished formulation.

Sources & references

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