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Ingredient · INCI reference

Atelocollagen

Atelocollagen is a purified, low-immunogenicity form of collagen with its terminal telopeptides removed, used in cosmetics as a film-forming, skin-conditioning ingredient.

What it is

This ingredient is collagen that has been enzymatically treated to remove the telopeptide regions at the ends of the molecule, which lowers its potential to provoke an immune response and improves its handling in formulation. In cosmetics it behaves as a large, water-binding protein that can leave a smoothing film on the skin surface. It is used in leave-on products including serums and sunscreens for its conditioning feel.

Safety & warnings

The removal of telopeptides is intended to reduce immunogenicity, and atelocollagen is generally well tolerated in topical use. As a large water-soluble protein it is not considered comedogenic. There is no fragrance-allergen concern associated with it.

Origin & sourcing

Derived from animal-source collagen (commonly bovine or marine) that is enzymatically processed to remove the telopeptide ends, yielding a purified protein.

History

Atelocollagen was developed for biomedical applications where reduced immunogenicity is important, and the same processing approach has been carried over into cosmetic use as a refined collagen ingredient.

Questions everyone asks

What makes atelocollagen different from ordinary collagen?

Its telopeptide end regions have been enzymatically removed, which lowers its potential to trigger an immune response and refines its behavior.

What does it do in a sunscreen?

It acts as a conditioning, film-forming protein that contributes a smooth feel; it does not provide UV protection.

Sources & references

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