Cydonia Oblonga Seed Extract — INCI reference

What it is

Cydonia Oblonga Seed Extract is derived from the seeds of the quince fruit (Cydonia oblonga Mill., family Rosaceae). The seeds yield a mucilage rich in water-soluble polysaccharides — primarily glucuronoxylan — that forms a protective film on skin. This film helps reduce transepidermal water loss and supports the skin barrier. The extract also contains phenolic acids (chlorogenic, neochlorogenic, caffeic), flavonoids such as quercetin, tannins, and amygdalin. These constituents contribute antioxidant and anti-inflammatory activity. Research in murine models shows topical application can suppress TARC production in keratinocytes, reducing inflammatory markers associated with atopic skin responses. Clinical studies report improved skin moisture, elasticity, and reduced erythema with no adverse effects in human volunteers over 12-week use.

Safety & warnings

No significant safety concerns are established for cosmetic use of the processed extract. Raw quince seeds contain amygdalin (~1.5%), which can release hydrogen cyanide if seeds are crushed and consumed in quantity; however, the extraction process for cosmetic-grade material renders this hazard irrelevant at use concentrations. No observable skin irritation was noted in published topical studies. No comedogenicity or sensitisation data flagging it as a common allergen has been reported. Persons with known Rosaceae (rose-family) fruit allergies may wish to exercise caution.

Origin & sourcing

Quince (Cydonia oblonga) is native to the Hyrcanian forests south of the Caspian Sea in Iran and has been cultivated since Neolithic times across West Asia and the Mediterranean. Seeds are a by-product of fruit processing; they are soaked in water to release the mucilaginous polysaccharides, which are then extracted, filtered, and concentrated or dried to produce the cosmetic ingredient.

History

Quince seeds have been used in traditional medicine and cosmetics for centuries across the Middle East and Europe for their mucilaginous, soothing properties. The ingredient appears in the EU CosIng database as Pyrus Cydonia Seed Extract (CAS 90106-03-9, EINECS 290-223-1). Modern research from the 2000s onward has characterised its polyphenol and mucilage composition, with peer-reviewed studies published between 2014 and 2024 confirming moisturising, anti-inflammatory, and skin-barrier functions.

Questions everyone asks

What does Cydonia Oblonga Seed Extract do for skin?

It forms a hydrating film from seed mucilage polysaccharides, helping retain moisture and support the skin barrier. Its phenolic compounds also provide antioxidant and anti-inflammatory benefits, making it useful in soothing, moisturising, and barrier-repair formulations.

Is quince seed extract safe for sensitive skin?

Available evidence suggests it is well tolerated. No skin irritation was observed in published topical studies at concentrations up to 1%, and a 12-week human trial reported no adverse effects. Its anti-inflammatory properties may make it suitable for reactive or stressed skin.

What is the difference between Cydonia Oblonga Seed Extract and Leaf Extract?

Both come from the quince plant, but seed extract is particularly rich in mucilage polysaccharides that provide film-forming and moisturising effects. Leaf extract is noted mainly for its flavonoid and tannin content with antioxidant and skin-conditioning activity.

Can quince seed extract help with atopic or inflammatory skin conditions?

Preclinical research in mice showed significant reduction of atopic dermatitis-like symptoms with topical quince seed ethanol extract, linked to suppression of inflammatory chemokines.