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Ingredient · INCI reference

Disodium Guanylate

Disodium Guanylate is the disodium salt of guanylic acid, a nucleotide derivative used in cosmetics as a skin-conditioning agent.

What it is

Disodium Guanylate is the sodium salt of guanosine monophosphate, a nucleotide best known as a savory flavor enhancer in food. In cosmetics it is used at low levels as a skin-conditioning ingredient, often paired with related nucleotide salts. In a sunscreen it acts as a minor supporting additive rather than a primary functional component.

Safety & warnings

Nucleotide salts are generally well tolerated in skin care at the low levels used. They are water soluble and not associated with comedogenicity.

Origin & sourcing

Typically produced by fermentation or enzymatic processing of nucleotide sources, then converted to the disodium salt.

Questions everyone asks

What is Disodium Guanylate doing in a sunscreen?

It is included at low levels as a skin-conditioning additive, often alongside related nucleotide salts.

Isn't this a food ingredient?

Yes, it is also used as a flavor enhancer in food, but in cosmetics it serves a conditioning role.

Sources & references

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