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Ingredient · INCI reference

Glucosyl Hesperidin

A water-soluble, enzymatically glucose-modified form of the citrus flavonoid hesperidin, used in skincare as an antioxidant and skin-conditioning agent.

What it is

Glucosyl Hesperidin is made by enzymatically attaching glucose units to hesperidin, a flavonoid found in citrus peel, which greatly increases its water solubility compared with the parent compound. The improved solubility makes it easier to formulate into water-based cosmetic systems. In sunscreens and serums it is used for its flavonoid antioxidant character and skin-conditioning properties.

Safety & warnings

It is regarded as well tolerated at cosmetic concentrations and is not a recognized fragrance allergen. Because it is water-soluble and not an oil, comedogenicity is not a typical concern.

Origin & sourcing

Semi-synthetic: hesperidin is sourced from citrus fruit (such as orange peel), then modified through an enzymatic glucose-transfer reaction to form the more soluble glucoside.

History

Glucosyl hesperidin was developed in Japan as a more soluble derivative of citrus hesperidin and has been used in both food and cosmetic applications.

Questions everyone asks

How does it differ from regular hesperidin?

Regular hesperidin is poorly water-soluble. Adding glucose makes glucosyl hesperidin far more soluble, so it blends more easily into water-based formulas.

Where does hesperidin come from?

Hesperidin is a flavonoid naturally found in citrus fruits, especially in the peel of oranges and related species.

Sources & references

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