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Ingredient · INCI reference

Glutamine

A naturally occurring amino acid used in skincare as a skin-conditioning and humectant ingredient.

Molecular structure

Formula C5H10N2O3

2D reference structure.

What it is

Glutamine is one of the standard amino acids that make up proteins in the body and is included in cosmetics as a small, water-soluble conditioning agent. In sunscreens and moisturizers it contributes to a smooth, hydrated skin feel and is often part of amino-acid blends. It is typically used at low concentrations.

Safety & warnings

As a common amino acid, glutamine is considered well tolerated and non-irritating at cosmetic use levels. It is not a recognized fragrance allergen and, being water-soluble rather than an oil, is not associated with comedogenicity.

Origin & sourcing

Glutamine for cosmetic use is generally produced by fermentation, yielding the L-form amino acid; it also occurs naturally in the body and in many proteins.

Questions everyone asks

What does glutamine do in skincare?

It acts as a water-soluble amino acid that conditions skin and supports hydration, often as part of an amino-acid blend in moisturizers and sunscreens.

Is glutamine the same as the body's glutamine?

Yes, it is the same amino acid found naturally in proteins and the body; cosmetic-grade material is usually made by fermentation.

Sources & references

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