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Ingredient · INCI reference

Hexacarboxymethyl Dipeptide-12

Hexacarboxymethyl Dipeptide-12 is a synthetic carboxymethylated dipeptide used as a skin-conditioning active in cosmetic formulations.

What it is

Hexacarboxymethyl Dipeptide-12 is a modified dipeptide in which the peptide backbone carries multiple carboxymethyl groups. It is included in leave-on skincare and sunscreen formulas as a conditioning agent intended to support the appearance of the skin. As a synthetic peptide derivative, it is used at low concentrations within finished products.

Safety & warnings

Peptide derivatives of this type are generally well tolerated in leave-on cosmetic use at the low levels typically employed. It is not a recognized fragrance allergen and is not an oil, so comedogenicity is not a relevant concern.

Origin & sourcing

Synthetic peptide derivative produced by chemical synthesis; the carboxymethyl substitution is added to a short dipeptide sequence.

Questions everyone asks

What is Hexacarboxymethyl Dipeptide-12 used for?

It is used as a skin-conditioning ingredient in leave-on skincare and sunscreen products, typically at low concentrations.

Is Hexacarboxymethyl Dipeptide-12 natural or synthetic?

It is a synthetic peptide derivative made by chemically modifying a short dipeptide with carboxymethyl groups.

Sources & references

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