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Ingredient · INCI reference

Hexapeptide-2

Hexapeptide-2 is a synthetic six-amino-acid peptide used in skincare and sunscreens as a skin-conditioning active.

What it is

Hexapeptide-2 is a short, synthetically produced peptide composed of a defined sequence of six amino acids. In sunscreens and treatment products it is included at low concentrations as a skin-conditioning ingredient, marketed as part of peptide-based formulas. Like most cosmetic peptides it is used in the water phase and contributes to the conditioning rather than the protective function of a product.

Safety & warnings

Cosmetic peptides such as hexapeptide-2 are generally well tolerated at the low levels used in formulas. It is not an oil and is not a recognized fragrance allergen, so comedogenicity and fragrance-allergen concerns do not apply; isolated individual sensitivity is possible as with any ingredient.

Origin & sourcing

It is a synthetic ingredient manufactured by controlled peptide synthesis to produce a consistent, defined amino-acid sequence.

Questions everyone asks

What is hexapeptide-2?

It is a synthetic peptide made of six amino acids, used in cosmetics as a skin-conditioning ingredient.

Why is it added to sunscreen?

It is included as a conditioning component of peptide-focused formulas rather than for UV protection itself.

Sources & references

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