Sunscreen Ranker Independent ranker
Ingredient · INCI reference

Histidine HCl

Histidine HCl is the hydrochloride salt of the amino acid histidine, used in cosmetics as a skin-conditioning ingredient.

What it is

Histidine HCl is the more soluble hydrochloride salt form of histidine, an amino acid that occurs naturally in skin. In cosmetic formulas it is used to condition the skin and can contribute to the amino-acid component of moisturizing systems. The salt form improves its handling and solubility in water-based formulas.

Safety & warnings

As a naturally occurring amino acid salt, histidine HCl is generally well tolerated in topical use and is not considered a common sensitizer.

Origin & sourcing

It is the hydrochloride salt of histidine, an amino acid; cosmetic-grade material is typically produced through fermentation or synthesis.

Questions everyone asks

What is histidine HCl?

It is the hydrochloride salt of the amino acid histidine, used in cosmetics as a skin-conditioning ingredient with improved water solubility.

Why use the HCl salt form?

The hydrochloride salt is more soluble and easier to incorporate into water-based formulas than the free amino acid.

Sources & references

Back to all ingredients