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Ingredient · INCI reference

Hydroxydecyl Ubiquinone

Hydroxydecyl Ubiquinone is a synthetic derivative of coenzyme Q10 (ubiquinone) used in cosmetics as an antioxidant and skin-conditioning ingredient.

What it is

Hydroxydecyl Ubiquinone is a structurally modified analog of coenzyme Q10, with a shortened hydroxylated side chain that alters its solubility and stability compared with native ubiquinone. It is used in skincare primarily for its antioxidant character, helping to support the skin against free-radical and oxidative stress. In sunscreens it acts as a supporting antioxidant rather than as a UV filter.

Safety & warnings

Hydroxydecyl Ubiquinone is generally well tolerated, though some users can experience irritation or sensitization, and it has been associated with allergic contact dermatitis in a minority of individuals; a patch test is reasonable for sensitive skin. It is colored and can lend a tint to formulas.

Origin & sourcing

Synthetic. It is a laboratory-produced analog of the naturally occurring coenzyme Q10 (ubiquinone), modified to change its side-chain structure.

History

This molecule is widely known by the name idebenone, which was originally developed and studied in a pharmaceutical context before being adopted as a cosmetic antioxidant.

Questions everyone asks

Is Hydroxydecyl Ubiquinone the same as coenzyme Q10?

It is a close synthetic relative. It is an analog of coenzyme Q10 with a modified side chain, and it is commonly known as idebenone.

What does it do in a sunscreen?

It works as an antioxidant that helps support the skin against oxidative stress. It is not a UV filter and does not provide SPF by itself.

Sources & references

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