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Ingredient · INCI reference

Nicotinamide Adenine Dinucleotide

Nicotinamide adenine dinucleotide (NAD) is a naturally occurring nicotinamide-based coenzyme used in skincare as a conditioning and antioxidant-style active.

What it is

NAD is a dinucleotide built from a nicotinamide unit and an adenine unit that functions as a central coenzyme in cellular energy metabolism. In cosmetic formulas it is included as a skin-conditioning agent, often alongside nicotinamide-family ingredients in products marketed for radiance and firmness. It is water-soluble and used at low levels within the leave-on bases of creams and sunscreens.

Safety & warnings

NAD is generally well tolerated in topical cosmetic use and is not a recognized fragrance allergen. As a water-soluble, non-oily ingredient it is not associated with comedogenicity. Individual sensitivity is always possible, so patch testing is reasonable for reactive skin.

Origin & sourcing

NAD is found in all living cells; the cosmetic ingredient is typically produced by biotechnological fermentation or chemical synthesis to yield a defined, high-purity material.

Questions everyone asks

What is NAD used for in sunscreen?

It is added as a skin-conditioning and antioxidant-style ingredient, usually in products positioned around radiance and firmness, rather than as a sunscreen filter.

Is NAD the same as niacinamide?

No. They are related members of the nicotinamide family, but NAD is a larger coenzyme molecule while niacinamide is the simpler vitamin form.

Sources & references

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