What it is
Octisalate is the 2-ethylhexyl ester of salicylic acid, a colorless oily liquid with a faint floral odor used as an organic UVB filter in sunscreens. The salicylate portion of the molecule absorbs ultraviolet light, while the branched ethylhexanol portion is a fatty alcohol that contributes emollient character and oil solubility. Because it is a good solvent for other filters, octisalate is frequently formulated to improve the affinity and reduce the photodegradation of less stable filters such as avobenzone and oxybenzone.
Spectrum coverage
UVB
Regional approval · max %
Safety & warnings
Salicylate sunscreen esters such as octisalate are generally regarded as well tolerated on skin and have historically been associated with low irritation. As an oil-phase ester it is more likely to suit those who tolerate emollient-rich formulas; individuals with a known sensitivity to salicylates may wish to be cautious. Regulators have in some cases requested additional data for several organic filters as part of ongoing review.
Origin & sourcing
Octisalate is a synthetic compound produced by the condensation (esterification) of salicylic acid with 2-ethylhexanol. It is not obtained from natural sources in the form used in cosmetics; the salicylate backbone shares chemistry with naturally occurring salicylates, but the cosmetic ingredient is manufactured.
History
Salicylate esters are among the older organic sunscreen agents, valued historically for their low irritation and good general safety. A 2007 cosmetic ingredient assessment reported that octyl salicylate and other salicylates had a good safety profile, and the material has long been used as a UVB absorber and as a stabilizing co-solvent for other filters.
Questions everyone asks
What does octisalate do in sunscreen?
It absorbs UVB light and, because it is oil-soluble, it also helps dissolve and stabilize other UV filters such as avobenzone, improving the overall formula.
Is octisalate the same as ethylhexyl salicylate?
Yes. Octisalate is the common name; ethylhexyl salicylate (2-ethylhexyl salicylate) is the INCI name for the same molecule.
Does octisalate provide UVA protection?
No. Octisalate absorbs mainly in the UVB range, so it is typically paired with separate UVA filters for broad-spectrum protection.