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Ingredient · INCI reference

Palmitoyl Tetrapeptide-10

A synthetic lipopeptide pairing a palmitic acid chain with a four-amino-acid peptide, used in skincare as a conditioning and soothing ingredient.

What it is

Palmitoyl Tetrapeptide-10 is a tetrapeptide linked to palmitic acid, which improves its compatibility with skin lipids. In cosmetics it is used as a leave-on conditioning peptide, often included in blends intended to support skin comfort and a smooth feel. It is used at very low concentrations.

Safety & warnings

Synthetic palmitoyl peptides are generally well tolerated at the trace levels used in leave-on products, with a low likelihood of irritation or sensitization.

Origin & sourcing

Synthetic; produced by peptide synthesis and conjugated to a palmitoyl (fatty acid) chain.

Questions everyone asks

What is the role of palmitoyl tetrapeptide-10?

It is a conditioning peptide used in leave-on skincare to support a smooth, comfortable feel; it is not a UV filter.

What does the palmitoyl part do?

The palmitic acid chain helps the peptide associate with skin lipids for better delivery in a formula.

Sources & references

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