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Ingredient · INCI reference

Palmitoyl Tripeptide-1

Palmitoyl tripeptide-1 is a synthetic lipidated signal peptide used in cosmetics as a skin-conditioning ingredient in products positioned for firmness and smoothness.

What it is

Palmitoyl tripeptide-1 is a three-amino-acid peptide (based on the GHK sequence) joined to palmitic acid to improve its affinity for the skin surface. It is used as a skin-conditioning agent and is frequently paired with other peptides in anti-aging-positioned formulas, including some sunscreens. It is used at very low concentrations.

Safety & warnings

Palmitoyl tripeptide-1 is generally well tolerated at the low levels used in cosmetics and has a good safety record. It is not a recognized fragrance allergen and is not associated with comedogenicity.

Origin & sourcing

Synthetic, made by peptide synthesis and conjugated to a palmitic-acid chain to enhance skin compatibility.

Questions everyone asks

What does palmitoyl tripeptide-1 do in a formula?

It acts as a skin-conditioning agent and is often combined with other peptides in products positioned for firmness and smoothness.

Is palmitoyl tripeptide-1 natural or synthetic?

It is synthetic, produced by peptide synthesis and then attached to a palmitic-acid chain.

Sources & references

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