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Ingredient · INCI reference

Pentapeptide-13

Pentapeptide-13 is a synthetic five-amino-acid peptide used in skincare as a conditioning ingredient marketed for signaling-type support of skin.

What it is

Pentapeptide-13 is a short chain of five amino acids produced by peptide synthesis for use in cosmetic formulations. Like other cosmetic peptides it is included as a skin-conditioning agent intended to support the appearance of smooth, well-maintained skin. It is typically used at low concentrations within the water phase of serums and creams.

Safety & warnings

Short synthetic peptides are generally well tolerated and are not recognized fragrance allergens or comedogenic. They are used at low levels, and irritation is uncommon, though individual sensitivity is always possible.

Origin & sourcing

Synthetic. It is manufactured through controlled peptide synthesis rather than extracted from a natural source.

Questions everyone asks

What is Pentapeptide-13?

It is a synthetic peptide made of five amino acids, used as a skin-conditioning ingredient in serums and creams.

Does Pentapeptide-13 protect against UV?

No. It is a conditioning peptide, not a UV filter; sun protection in a product comes from its listed sunscreen actives.

Sources & references

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