What it is
Proteases are enzymes that catalyze the breakdown of peptide bonds in proteins, and they are produced for cosmetic use by microbial fermentation or extracted from natural sources. In skin care they are included at controlled levels to help loosen and digest proteins on the skin surface, offering a gentle, enzyme-based approach to smoothing. In a sunscreen formula they typically appear as a minor functional or conditioning addition.
Safety & warnings
Proteolytic enzymes can be sensitizing in some individuals, and inhalation of enzyme dust is an occupational concern during manufacturing, though finished leave-on products use stabilized, low concentrations. People with sensitive or compromised skin may prefer to patch test enzyme-containing products.
Origin & sourcing
Most cosmetic proteases are produced by microbial fermentation; some are sourced from plants or other natural materials.
Questions everyone asks
What does protease do in skin care?
It is a protein-digesting enzyme used at low levels to gently help loosen surface skin proteins, supporting mild exfoliation.
Where does cosmetic protease come from?
It is most often produced by microbial fermentation, with some grades sourced from plants or other natural materials.