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Ingredient · INCI reference

Sh-Polypeptide-1

sh-Polypeptide-1 is a synthetic, biotechnology-produced polypeptide used in skincare as a skin-conditioning active.

What it is

sh-Polypeptide-1 is a synthetic human-identical polypeptide produced by biotechnology, with the "sh" prefix denoting a synthetic version of a human-type protein sequence. In cosmetics it is used as a skin-conditioning active. When it appears in sunscreens it serves a conditioning purpose and contributes nothing to UV protection.

Safety & warnings

Used at low levels and generally well tolerated. As a defined synthetic polypeptide it is not associated with comedogenicity and avoids the variability seen with crude botanical or animal-derived materials.

Origin & sourcing

Synthetic; produced through biotechnology such as recombinant fermentation rather than isolated from natural tissue.

Questions everyone asks

What is sh-Polypeptide-1?

It is a synthetic human-identical polypeptide made by biotechnology and used as a skin-conditioning active in skincare.

Does it offer sun protection?

No. It is a conditioning ingredient and does not act as a UV filter.

Sources & references

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