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Ingredient · INCI reference

Tetracarboxymethyl Hexanoyl Dipeptide-12

A synthetic dipeptide derivative used in cosmetics as a skin-conditioning active marketed for supporting skin appearance.

What it is

Tetracarboxymethyl Hexanoyl Dipeptide-12 is a synthetic peptide ingredient consisting of a short dipeptide that has been modified with a fatty acyl group and carboxymethyl groups. Like other cosmetic peptides it is used at low concentrations as a skin-conditioning active intended to support the look and feel of the skin. It appears in some treatment-oriented skincare and sunscreen formulas as a featured ingredient.

Safety & warnings

Cosmetic peptides of this kind are generally well tolerated and not commonly associated with irritation or sensitization at the low levels used.

Origin & sourcing

Synthetic. It is manufactured through peptide synthesis and subsequent chemical modification rather than being extracted from a natural source.

Questions everyone asks

Is this ingredient a peptide?

Yes. It is a synthetic dipeptide derivative modified with acyl and carboxymethyl groups, used as a skin-conditioning active.

Is it natural or synthetic?

It is synthetic, produced by peptide synthesis and chemical modification.

Sources & references

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