Sunscreen Ranker Independent ranker
LA
La Roche-Posay

Anthelios UVmune 400 Cream SPF 50+

SPF 50+ Invisible No white cast — chemical/hybrid filters that disappear on skin. EU Europe global Formulation variant: global. Region-specific reformulations are tracked as separate products.

Robust modern EU filter suite, no fragrance, elegant fluid texture; alcohol denat positioned third tempers sensitive-skin score.

◐ CHEM Chemical filters Chemical filters — Organic filters absorb UV. Cosmetically elegant; filter selection matters. ((· BS Broad spectrum Broad spectrum — Blocks UVA + UVB across the full sun-damage spectrum. F F-FREE Fragrance-free Fragrance-free — No added fragrance or perfume — lower irritation risk for reactive skin.
79.6
Composite
Composite score · independent
Ranks #358 of 1558 in the current catalogue. Robust modern EU filter suite, no fragrance, elegant fluid texture; alcohol denat positioned third tempers sensitive-skin score.
Composite is a weighted blend: UV 25% · Modernity 10% · Sensitivity 15% · Environment 10% · Elegance 15% · Health 25%.
Verdict Should you buy it?

The flagship EU Uvmune cream stacks Mexoryl 400 with bemotrizinol, Uvinul T 150 and a full long-UVA toolkit for strong, modern protection. Alcohol denat sits third in the list, tempering wearability for reactive skin.

Pros
  • Eight-filter modern EU system
  • Mexoryl 400 covers long UVA
  • Fragrance-free formulation
  • Elegant fluid-cream texture
  • Tocopherol and stabilizing antioxidants
Cons
  • Alcohol denat high in the list
  • Triethanolamine present
  • No PA rating provided
  • Not suitable for alcohol-averse skin

Who it's for: Buyers wanting top-tier UVA-I coverage in a refined cream and willing to accept denatured alcohol for the finish.

01 Score breakdown
UV protection How well the product blocks UVA + UVB across the spectrum at the stated SPF/PA. 85
Filter modernity Penalises legacy filters (octinoxate, oxybenzone); rewards photostable next-gen filters. 86
Sensitivity safety Risk for reactive skin — fragrance, alcohol, known sensitisers. 58
Reef / env. safety Reef toxicity, biodegradability of UV filters and surfactants. 100
Cosmetic elegance Spread, finish, white-cast, comfort on skin. 80
Health safety Endocrine concerns, systemic absorption signals across the formula. 76
02 Composition · key UV filters 8 filters resolved
UVB 290–320nm UVB (290–320nm) — covered UVA-II 320–340nm UVA-II (320–340nm) — covered UVA-I 340–400nm UVA-I (340–400nm) — covered
Octisalate Legacy Older organic filter. Photostable in combination; some literature concerns.
Uvinul T 150 Modern Next-gen photostable filter; low irritation profile.
Bemotrizinol Modern Next-gen photostable filter; low irritation profile.
Mexoryl XL Modern Next-gen photostable filter; low irritation profile.
Avobenzone Legacy Older organic filter. Photostable in combination; some literature concerns.
Mexoryl 400 (MCE) Modern Next-gen photostable filter; low irritation profile.
Uvinul A Plus Modern Next-gen photostable filter; low irritation profile.
Ecamsule (Mexoryl SX) Modern Next-gen photostable filter; low irritation profile.
03 At-a-glance facts
Protection
Filter type Mineral filters (zinc oxide, titanium dioxide) sit on skin and reflect UV. Chemical filters absorb UV. Hybrid blends both.
Chemical
Broad spectrum Protects across both UVA and UVB ranges. UVA causes aging and deeper damage; UVB causes burns.
Yes
Formulation & feel
Texture How the formula feels at application — milk, gel, cream, spray, stick, essence, lotion, powder, or cushion.
Cream
Finish How the formula looks on skin once dry: matte, natural, dewy, or glowy.
Natural
Tinted Adds sheer pigment (iron oxides) that masks the white cast common to mineral filters and gives a skin-tone finish.
No
Fragrance-free No synthetic perfume added. Not FDA-defined in the US; the EU requires 'Parfum' + the 26 named allergens on the label. 'Unscented' differs — may contain masking fragrance. Botanical oils still scent.
Yes
Alcohol-free No drying short-chain alcohols (alcohol denat., SD alcohol, ethanol). Does not refer to fatty alcohols like cetyl or stearyl alcohol, which are emollients.
No
04 Full ingredient list (INCI) 27 ingredients
MODERN FILTER 6 LEGACY FILTER 2 MINERAL FILTER 0 ADDED FRAGRANCE 0 NATURAL FRAGRANCE 0 ALCOHOL 1 WATCH 0 ACTIVE 2
Water·Diisopropyl Sebacate· Alcohol Denat. Drying short-chain alcohol — can compromise the skin barrier and disturb the film if used in high amounts. · Ethylhexyl Salicylate Octisalate — older filter; well-tolerated. · Ethylhexyl Triazone Uvinul T 150 — high-efficiency UVB filter. · Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine Tinosorb S — broad-spectrum, very photostable. ·Diisopropyl Adipate·Peg-8·Dipropylene Glycol·C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer· Glycerin Humectant — the workhorse hydrator. · Drometrizole Trisiloxane Mexoryl XL ·Aluminum Starch Octenylsuccinate· Butyl Methoxydibenzoylmethane Avobenzone — UVA filter, needs stabilisation. · Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate Mexoryl 400 (MCE) ·Silica· Tocopherol Vitamin E — antioxidant. · Diethylamino Hydroxybenzoyl Hexyl Benzoate Uvinul A Plus — modern photostable UVA filter. ·Acrylates Copolymer·Acrylates/C10-30 Alkyl Acrylate Crosspolymer·Caprylyl Glycol·Hydroxyacetophenone·Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate·Sodium Polyacrylate· Terephthalylidene Dicamphor Sulfonic Acid Ecamsule (Mexoryl SX) ·Triethanolamine·Trisodium Ethylenediamine Disuccinate
Source: brand-published INCI. Last verified 19 Jun 2026. Show in detail
01 Water Water
02 Diisopropyl Sebacate Diisopropyl Sebacate
03 Alcohol Denat. ALCOHOL Drying short-chain alcohol — can compromise the skin barrier and disturb the film if used in high amounts.
04 Ethylhexyl Salicylate LEGACY FILTER Octisalate — older filter; well-tolerated.
05 Ethylhexyl Triazone MODERN FILTER Uvinul T 150 — high-efficiency UVB filter.
06 Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine MODERN FILTER Tinosorb S — broad-spectrum, very photostable.
07 Diisopropyl Adipate Diisopropyl Adipate
08 Peg-8 PEG-8
09 Dipropylene Glycol Dipropylene Glycol
10 C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer
11 Glycerin ACTIVE Humectant — the workhorse hydrator.
12 Drometrizole Trisiloxane MODERN FILTER Mexoryl XL
13 Aluminum Starch Octenylsuccinate Aluminum Starch Octenylsuccinate
14 Butyl Methoxydibenzoylmethane LEGACY FILTER Avobenzone — UVA filter, needs stabilisation.
15 Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate MODERN FILTER Mexoryl 400 (MCE)
16 Silica Silica
17 Tocopherol ACTIVE Vitamin E — antioxidant.
18 Diethylamino Hydroxybenzoyl Hexyl Benzoate MODERN FILTER Uvinul A Plus — modern photostable UVA filter.
19 Acrylates Copolymer Acrylates Copolymer
20 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Acrylates/C10-30 Alkyl Acrylate Crosspolymer
21 Caprylyl Glycol Caprylyl Glycol
22 Hydroxyacetophenone Hydroxyacetophenone
23 Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
24 Sodium Polyacrylate Sodium Polyacrylate
25 Terephthalylidene Dicamphor Sulfonic Acid MODERN FILTER Ecamsule (Mexoryl SX)
26 Triethanolamine Triethanolamine
27 Trisodium Ethylenediamine Disuccinate Trisodium Ethylenediamine Disuccinate